Recent progress of nanogenerators acting as biomedical sensors in vivo

论文摘要

Since the nanogenerator（NG） was invented in 2006, it has been successfully developed and utilized to harvest various forms of mechanical energy in vivo. The NGs promote the progress of self-powered biomedical devices. Moreover, NGs can also be used as sensors to detect a variety of important physiological signals, which brings us closer to real-time, high-fidelity monitoring of physical and pathological information. This paper summarizes the in vivo applications of NGs as biomedical sensors, including in cardiac sensors, respiration sensors, blood pressure sensors, gastrointestinal sensors and bladder sensors.However, there are still many challenges in using NGs as sensors in vivo. For example, how can we minimize and encapsulate the NGs, how can we increase the stability and reliability during long-term detection, and how can we establish a corresponding relationship between the NG’s electrical output and the physiological signals. It is also critical to follow the medical principles more closely in the development of self-powered sensors in the future. We believe that the self-powered sensors would promote the development of the next-generation healthcare monitoring systems.

论文目录

• 1. Introduction
• 2. Working mechanism of NG
•   2.1. PENG
•   2.2. TENG
• 3. NG as biomedical sensors
•   3.1. Cardiac sensor
•   3.2. Respiration sensor
•   3.3. Blood pressure sensor
•   3.4. Gastrointestinal sensor
•   3.5. Bladdar sensor
• 4. Discussion and conclusions
• Conflict of interest
• Author contributions
• Appendix A.Supplementary data

文章来源

类型: 期刊论文

作者: Jinyan Sun,Anping Yang,Chaochao Zhao,Fang Liua,Zhou Li

来源: Science Bulletin 2019年18期

年度: 2019

分类: 基础科学,工程科技Ⅱ辑,信息科技

专业: 电力工业,自动化技术

单位: Department of Biomedical Engineering, School of Medical Engineering, Foshan University,Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences,Center on Nanoenergy Research, School of Physical Science and Technology, Guangxi University

基金: supported by the National Key Research and Development Program of China (2016YFA0202703),the Scientific Research Foundation for Advanced Scholars of Foshan University (Gg07136,Gg07164),the Key Platform and Scientific Research Project of Guangdong Provincial Education Department (2018KTSCX246),the Science and Technology Planning Project of Guangdong Province (2018B030331001),the National Natural Science Foundation of China (61875015,31571006,81570202,and 8157037),the Beijing Natural Science Foundation (2182091),the National Youth Talent Support Program

分类号: TM31;TP212

页码: 1336-1347

总页数: 12

文件大小: 6030K

下载量: 36