论文摘要
A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for the gelation were hydrogen bonding and π-π stacking. This molecular hydrogel exhibited satisfied photocleavage at C-N bond in 7-amino coumarin with the light irradiation (365 nm,77.5 mW/cm2). The promising photo-triggered drug release of antineoplastics cytarabine hydrochloride has been obtained, due to the photocleavage motived gel-sol transition.
论文目录
文章来源
类型: 期刊论文
作者: Qihong Liu,Hao Wang,Guotao Li,Miaochang Liu,Jinchang Ding,Xiaobo Huang,Wenxia Gao,Huayue Wu
来源: Chinese Chemical Letters 2019年02期
年度: 2019
分类: 工程科技Ⅰ辑
专业: 有机化工
单位: College of Chemistry and Materials Engineering, Wenzhou University
基金: financial support from the National Natural Science Foundation of China (Nos. 21672164,21372177)
分类号: TQ427.26;TQ460.1
页码: 485-488
总页数: 4
文件大小: 955K
下载量: 18