The VfmIH two-component system modulates multiple virulence traits in Dickeya zeae

论文摘要

Pathogenic bacteria Dickey a zeae strain EC1 produces a family of antibiotics-like phytotoxins named zeamines,which are encoded by the zms gene cluster and critical for bacterial virulence.In this study,we identified a zeamine deficient mutant with Tn5 inserted in a gene encoding a two-component system（TCS） sensor histidine kinase（HK）.Bioinformatics analysis showed that this kinase gene is the homologue of the vfml gene of D.dadantii strain 3 937.Similar to the case of D.dadantii 3 937,a homologue of vfmH encoding a response regulator（RR） is located at the vicinity of vfml and sharing the same operon.Deletion in—frame of either vfmI or vfmH resulted in significantly reduced production of zeamines and cell wall degrading enzymes（CWDEs）,and mitigated the bacterial virulence on rice seeds and potato tubers.RNA-seq and Q-RT PCR analysis of D.zeae EC1 and the mutant of VfmH showed that the TCS positively modulated the transcriptional expression of a range of virulence genes,including zms,T1 SS,T2 SS,T6 SS,flagellar and CWDEs genes.In D.dadantii 3937,VfmH protein was shown to interact with the promoters of vfmA and vfmE to affect the transcription.This study found that the VfmH protein not merely could directly interact with the promoters of vfmA and vfmE but also interact with the promoters of vfmF to affect the transport of Vfm signals.

论文目录

文章来源

类型: 国内会议

作者: Lv Mingfa,Hu Ming,Li Peng,Jiang Zide,Zhou Jianuan,Zhang Lianhui

来源: 中国植物病理学会2019年学术年会 2019-07-20

年度: 2019

分类: 基础科学,农业科技

专业: 生物学,植物保护

单位: Guangdong Province Key Laboratory of Microbial Signals and Disease Control,Integrative Microbiology Research Centre,South China Agricultural UniversityMinistry of Education Key Laboratory for Ecology of Tropical Islands,College of Life Sciences,Hainan Normal University

分类号: S432.1

DOI: 10.26914/c.cnkihy.2019.020370

页码: 355

总页数: 1

文件大小: 45k

下载量: 11

相关论文文献

• [1].Rat CC chemokine receptor 4 is the functional homologue of human CC chemokine receptor 4 and can interact with human CCL17 and CCL22[J]. Chinese Science Bulletin 2010(14)
• [2].Electromagnetic metasurfaces: from concept to applications[J]. Science Bulletin 2019(12)
• [3].Protein Interaction Between p53 and △113p53 Is Required for the Anti-Apoptotic Function of △113p53[J]. Journal of Genetics and Genomics 2014(02)
• [4].SOCIETY[J]. Beijing Review 2019(17)
• [5].Systematic study of Nd~(3+) on structural properties of ZnO nanocomposite for biomedical applications; in-vitro biocompatibility,bioactivity, photoluminescence and antioxidant properties[J]. Journal of Rare Earths 2019(05)
• [6].SPH Numerical Modeling for the Wave–Thin Structure Interaction[J]. China Ocean Engineering 2018(02)
• [7].Global Tyre Development Trends[J]. 中国橡胶 2011(08)
• [8].We Chat Will Rock You[J]. ChinAfrica 2015(06)
• [9].Living With the World[J]. China & Africa 2013(05)
• [10].How can the neutrino interact with the electromagnetic field?[J]. Chinese Physics C 2018(01)
• [11].Murine Cytomegalovirus IE3 Protein Interacts with Ankrd17[J]. Journal of Huazhong University of Science and Technology(Medical Sciences) 2011(03)
• [12].Chinese Communication Styles[J]. Beijing Review 2014(02)
• [13].Living With the World[J]. Beijing Review 2013(16)
• [14].Binary black hole systems do not interact in the Kastor-Traschen spacetime[J]. Science China(Physics,Mechanics & Astronomy) 2019(04)
• [15].Analysis of Cultural Influence on Emotions[J]. 学术界 2015(10)
• [16].Construction of microenvironmental biointerfaces[J]. 医用生物力学 2010(S1)
• [17].Sisyphus' s Boulder:An Interpretation of Work[J]. 海外英语 2014(11)
• [18].Optical Tamm state polaritons in a quantum well microcavity with gold layers[J]. Chinese Physics B 2012(05)
• [19].Do deposed adult male Sichuan snub-nosed monkeys Rhinopithecus roxellana roam as solitary bachelors or continue to interact with former band members?[J]. Current Zoology 2009(03)
• [20].Microenvironmental biomaterials[J]. 医用生物力学 2009(S1)
• [21].Poly(1-vinylimidazole) Prospects in Gene Delivery[J]. Chinese Journal of Polymer Science 2019(07)
• [22].American Association for Cancer Research NEW HORIZONS IN CANCER RESEARCH[J]. Chinese Journal of Cancer 2017(10)
• [23].The K Domain Mediates Homologous and Heterologous Interactions Between FLC and SVP Proteins of Brassica juncea[J]. Horticultural Plant Journal 2015(01)
• [24].Scheme for direct measurement of Wigner function in two-mode cavity QED driven by classical fields[J]. Chinese Physics B 2010(12)
• [25].Syntheses,Characterization,and Crystal Structures of Three New Divalent Metal Sulfonates[J]. 结构化学 2009(05)
• [26].A Study on Typical Features of E-Discourse in Chinese[J]. 海外英语 2016(04)
• [27].Particles inside electrolytes with ion-specific interactions, their effective charge distributions, and effective interactions[J]. Chinese Physics B 2016(10)
• [28].Localizing object parts in 3D from a single image[J]. Science China(Information Sciences) 2019(07)
• [29].Mechanisms and Effects on HBV Replication of the Interaction between HBV Core Protein and Cellular Filamin B[J]. Virologica Sinica 2018(02)
• [30].Man-machine Relationship Analysis Based on Dashboard Similar Structure Design[J]. Journal of Landscape Research 2016(01)