Two Novel Metal Coordination Polymers:Anticancer Activity in Human Angioneoplasm Cells

论文摘要

Two new coordination polymers, namely {[Cu（CPTD）（HCOO）]（H2O）4}n（1, HCPTD= 4?-（4-Carboxyphenyl）-2,2?:6?,2??-terpyridine） and {[Dy3（NTB）3（NMF）2（H2O）]n（NMF）3}n（2,H3NTB = 4,4?,4??-nitrilotribenzoic acid, NMF = N-methylformamide） have been successfully constructed under solvothermal conditions. The structures of the two complexes have been successfully determined by single-crystal X-ray diffraction. In addition, in vitro antitumor activities of compounds 1 and 2 on three human angioneoplasm cells（MOLP-2, RPMI8226 and MM1 S）were further determined and the results show that the two compounds showed promising activity.

论文目录

• 1 INTRODUCTION
• 2 EXPERIMENTAL
•   2.1 Apparatus and materials
•   2.2 Synthesis and characterization of compounds 1 and 2
•   2.3 Crystal structure determination
•   2.4 Antitumor activity
• 3 RESULTS AND DISCUSSION
•   3.1 Molecular structure
•   3.2 IR analysis
•   3.3 Antitumor activity
• 4 CONCLUSION

文章来源

类型: 期刊论文

作者: 马小五,董静,张建鑫,吴文芳,冉红,张平洋

来源: Chinese Journal of Structural Chemistry 2019年07期

年度: 2019

分类: 工程科技Ⅰ辑

专业: 化学,有机化工

单位: Department of Cardiovascular Ultrasound, Nanjing Hospital Affiliated to Nanjing Medical University, Nanjing First Hospital

分类号: O641.4;TQ460.1

DOI: 10.14102/j.cnki.0254-5861.2011-2190

页码: 1146-1151

总页数: 6

文件大小: 474K

下载量: 12