Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review

论文摘要

Magnesium（Mg） alloys possess comparable physical and mechanical properties to bone, making them an outstanding candidate of implant materials for bone fracture treatment. In addition to the excellent biocompatibility, and bioactivity, the engagement of Mg alloys is key for a number of biological functionalities in the human body. The unique biodegradation nature of Mg alloy implants implies that it may not require a secondary removal procedure when the expected supporting tasks accomplish, as they may simply and safely "disappear" over time. Nonetheless, the demonstrated drawback of potentially rapid degradation, is an issue that must be addressed appropriately for Mg implants and is consequently given unique attention in this review article. Herein, the critical criteria and the state-of-the-art strategies for controlling the degradation process of Mg alloys are reported. Furthermore, future developments of biodegradable Mg and its alloys systems with satisfactory specifications for clinical trials and deployment,are discussed. This review aims to provide information to materials scientists and clinical practitioners in the context of developing practical biodegradable Mg alloys.

论文目录

文章来源

类型: 期刊论文

作者: Ming-Shi Song,Rong-Chang Zeng,Yun-Fei Ding,Rachel W.Li,Mark Easton,Ivan Cole,Nick Birbilis,Xiao-Bo Chen

来源: Journal of Materials Science & Technology 2019年04期

年度: 2019

分类: 工程科技Ⅰ辑,医药卫生科技

专业: 金属学及金属工艺,生物医学工程

单位: School of Engineering,RMIT University,Department of Materials Science and Engineering,Monash University,College of Materials Science and Engineering,Shandong University of Science and Technology,School of Mechanical Engineering,Huaihai Institute of Technology,The Medical School,The Australian National University

基金: financial support through VC Fellowships and Enabling Capability Platform for Advanced Manufacturing and Fabrication,Financial support from the Australian Research Council through DECRA (DE130100090) and Linkage Schemes (LP150100343) is also gratefully acknowledged,support by the National Natural Science Foundation of China (51571134),Shandong University of Science and Technology Research Fund (2014TDJH104),supported by the Natural Science Foundation of the Higher Education Institute of Jiangsu Province (17KJB430003)

分类号: R318.08;TG146.22

页码: 535-544

总页数: 10

文件大小: 1388K

下载量: 29

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