导读:本文包含了心安宁滴鼻剂论文开题报告文献综述、选题提纲参考文献及外文文献翻译，主要关键词:心安,心绞痛,药疗法,不稳定性,冠状动脉,心肌,持续性。
心安宁滴鼻剂论文文献综述
王忠良,钱士明[1]（2007）在《心安宁滴鼻剂预处理对垂体后叶素致实验大鼠急性心肌缺血的实验研究》一文中研究指出1实验材料1·1实验动物Wistar大鼠体重230g~270g,雌雄各半,共40只,由南京中医药大学实验动物中心提供。1·2实验药物及试剂心安宁滴鼻剂(由肉桂、党参、冰片、炙甘草、当归、葛根、酸枣仁等组成,每毫升相当于生药6g,南京中医药大学制剂室提供)(本文来源于《中国中医基础医学杂志》期刊2007年01期）
王忠良,钱士明,张寒梅[2]（2006）在《Effect of Xin’anning Nasal Drop (心安宁滴鼻剂) in Treating Coronary Heart Disease with Unstable Angina Pectoris》一文中研究指出Objective: To observe the clinical efficacy of Xin’anning Nasal Drop (XAND, 心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris (CHD-UAP). Methods: Sixty patients with CHD-UAP were assigned, according to the randomizing number table, to two groups, the control group treated with conventional Western medicine, and the treated group treated with conventional Western medicine plus XAND. The clinical efficacy and the changes of S-T segment in resting EKG and total ischemia burden (TIB) in 24-h dynamic EKG were observed. Results: The clinical efficacy, including the effect of angina alleviation, its initiation, and the effect of TCM syndrome score reduction, were significantly superior in the treated group to those in the control group ( P< 0.05 or P< 0.01). The degree and extent of myocardial ischemia were significantly improved in both groups ( P< 0.01), but the improvement in the treated group was better than that in the control group ( P< 0.05). Moreover, it was worth mentioning that the immediate effect in the treated group was better than that in the control group, and the reduction of TIB, the improvement in heart rate and myocardial oxygen consumption (immediately after the first administration or by the end of the therapeutic course), and systolic blood pressure after treatment in the former were all superior to those in the latter, showing significant difference ( P< 0.05 or P< 0.01). Conclusion: XAND has a quick effect in alleviating angina in patients with CHD-UAP, and it is worthy of further studies and spreading in clinical practice.(本文来源于《Chinese Journal of Integrated Traditional and Western Medicine》期刊2006年04期）
王忠良,钱士明,张寒梅[3]（2005）在《心安宁滴鼻剂治疗冠心病不稳定型心绞痛的临床研究》一文中研究指出目的:观察心安宁滴鼻剂治疗冠心病不稳定型心绞痛的临床疗效。方法:60例随机分为对照组(常规西药治疗)和治疗组,后者在常规西药治疗基础上加用心安宁滴鼻剂;观察临床疗效、静息心电图ST段变化和24小时动态心电图心肌缺血总负荷(TIB)变化。结果:心安宁滴鼻剂治疗不稳定型心绞痛起效迅速、疗效显着,具有抗心肌缺血作用。结论:心安宁滴鼻剂是一种防治不稳定型心绞痛的新型速效中药制剂。(本文来源于《湖北中医杂志》期刊2005年12期）
杨志新[4]（2004）在《心安宁滴鼻剂治疗持续性房颤的临床研究》一文中研究指出本文以中医基础理论为指导，结合西医学认识，提出了心房颤动的中医学病机新观点，认为心气亏虚、心阳亏虚心失所养是本病的发病前提和基础，而痰淤阻络、心脉不畅是本病的病机关键。并据此提出了益气温阳，祛淤化痰通络的基本治疗大法。心安宁滴鼻剂是导师钱士明教授的经验有效处方，蕴涵了这一病机治法思想。通过初步的临床试验研究，发现心安宁滴鼻剂治疗持续性房颤起效迅速、疗效显着，配合西药治疗组心电图改善有效率达90.48％临床症状改善有效率达95.2％明显由于对照组，初步推断心安宁滴鼻剂具有改善心肌供血和心肌细胞的电稳定性；类β—肾上腺素能受体阻滞样作用，减慢心率，降低血压，降低心肌耗氧量；抗血小板聚集；调脂、抗炎等作用。结果表明心安宁滴鼻剂是防治持续性房颤的一种新型速效制剂，值得进一步研究以推广应用于临床。(本文来源于《南京中医药大学》期刊2004-05-01）
杨志新,钱士明[5]（2004）在《心安宁滴鼻剂治疗持续性房颤临床观察》一文中研究指出目的 :观察心安宁滴鼻剂疗效。方法 :对照组服用阿斯匹林 ,治疗组加服心安宁滴鼻剂 ,观察治疗前后心电图、心率及症状改善情况。结果 :两组比较 ,有效率差别无显着意义 ,但心率和症状改善积分及起效时间差异有显着意义。结论 :中药心安宁滴鼻剂是一种比较理想的可用于防治房颤的药物。(本文来源于《河南中医学院学报》期刊2004年01期）
史爱武[6]（2001）在《心安宁滴鼻剂治疗不稳定性心胶痛的临床研究及机理探讨》一文中研究指出本文根据中医理论和导师的临床实践，总结了用心安宁滴鼻剂治疗不稳定性心绞痛的临床研究，认为本病基本病理以阳（气）虚为本，脉络瘀阻为标，虚实夹杂，相互为患。确立温阳益气，行瘀通络的基本治疗大法。据此研制成心安宁滴鼻剂。临床研究结果表明心安宁缓解心绞痛总有效率为93.3％，速效止痛的总起效率为93.3％，心电图改善总有效率为66.7％，优于对照组的60.0％、63.3％和43.3％，24小时动态心电图心肌缺血总负荷的改善明显优于对照组；在调血脂、抗血栓形成、改善血液流变学等方面亦有良好作用，较对照组为优；初步观察了不稳定性心绞痛患者血浆ET、NO的含量，心安宁能减少ET的分泌，提高NO的含量，具有一定的保护血管内皮的作用，与对照组比较为优。表明心安宁滴鼻剂对不稳定性心绞痛具有良好的防治作用，是一新的有效的中药速效制剂。(本文来源于《南京中医药大学》期刊2001-04-01）
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Objective: To observe the clinical efficacy of Xin’anning Nasal Drop (XAND, 心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris (CHD-UAP). Methods: Sixty patients with CHD-UAP were assigned, according to the randomizing number table, to two groups, the control group treated with conventional Western medicine, and the treated group treated with conventional Western medicine plus XAND. The clinical efficacy and the changes of S-T segment in resting EKG and total ischemia burden (TIB) in 24-h dynamic EKG were observed. Results: The clinical efficacy, including the effect of angina alleviation, its initiation, and the effect of TCM syndrome score reduction, were significantly superior in the treated group to those in the control group ( P< 0.05 or P< 0.01). The degree and extent of myocardial ischemia were significantly improved in both groups ( P< 0.01), but the improvement in the treated group was better than that in the control group ( P< 0.05). Moreover, it was worth mentioning that the immediate effect in the treated group was better than that in the control group, and the reduction of TIB, the improvement in heart rate and myocardial oxygen consumption (immediately after the first administration or by the end of the therapeutic course), and systolic blood pressure after treatment in the former were all superior to those in the latter, showing significant difference ( P< 0.05 or P< 0.01). Conclusion: XAND has a quick effect in alleviating angina in patients with CHD-UAP, and it is worthy of further studies and spreading in clinical practice.
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心安宁滴鼻剂论文参考文献
[1].王忠良,钱士明.心安宁滴鼻剂预处理对垂体后叶素致实验大鼠急性心肌缺血的实验研究[J].中国中医基础医学杂志.2007
[2].王忠良,钱士明,张寒梅.EffectofXin’anningNasalDrop(心安宁滴鼻剂)inTreatingCoronaryHeartDiseasewithUnstableAnginaPectoris[J].ChineseJournalofIntegratedTraditionalandWesternMedicine.2006
[3].王忠良,钱士明,张寒梅.心安宁滴鼻剂治疗冠心病不稳定型心绞痛的临床研究[J].湖北中医杂志.2005
[4].杨志新.心安宁滴鼻剂治疗持续性房颤的临床研究[D].南京中医药大学.2004
[5].杨志新,钱士明.心安宁滴鼻剂治疗持续性房颤临床观察[J].河南中医学院学报.2004
[6].史爱武.心安宁滴鼻剂治疗不稳定性心胶痛的临床研究及机理探讨[D].南京中医药大学.2001