Cryo-EM structure of yeast 90S pre-ribosome before A0 pre-rRNA cleavage

Cryo-EM structure of yeast 90S pre-ribosome before A0 pre-rRNA cleavage

论文摘要

<正>Formation of the 90S pre-ribosome before 5’ external transcribed spacer (5’ ETS) A0cleavage (A0-intact 90S) is a key event in the biogenesis of 40S small subunit ribosome (SSU).Using cryo-EM, a plasmid-derived 90S pre-ribosome (P-90S) which represents the A0-intact 90S was solved at 4.8?overall resolution (with a core map solved at 3.9?). Two states of the P-90S which are termed as closed state and open state were isolated by local 3D classification. We found

论文目录

文章来源

类型: 国内会议

作者: Yi-fei DU,Wei-dong AN,Ke-qiong YE

来源: 第六届全国冷冻电子显微学与结构生物学专题研讨会 2019-06-16

年度: 2019

分类: 基础科学

专业: 生物学

单位: Key Laboratory of RNA Biology, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences,University of Chinese Academy of Sciences

分类号: Q617

DOI: 10.26914/c.cnkihy.2019.038812

页码: 68

总页数: 1

文件大小: 118k

下载量: 4

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Cryo-EM structure of yeast 90S pre-ribosome before A0 pre-rRNA cleavage
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