Cryo-EM Structure of the origin recognition complex bound to the essential elements of ARS DNA

Cryo-EM Structure of the origin recognition complex bound to the essential elements of ARS DNA

论文摘要

<正>The six-subunit origin recognition complex (ORC) binds to DNA to mark the site for the initiation of replication in eukaryotes. Despite the high conservation of ORC in protein sequence among eukaryotes, its selectivity for replicators varies from species to species. The underlying molecular mechanism for this divergence of ORC in origin selectivity remains poorly understood.

论文目录

文章来源

类型: 国内会议

作者: Yuan-liang ZHAI,Ning-ning LI,Wai Hei LAM,Jia-xuan CHENG,Claire LEE,Yong-qian ZHAO,Ning GAO,Bik-Kwoon TYE

来源: 第六届全国冷冻电子显微学与结构生物学专题研讨会 2019-06-16

年度: 2019

分类: 基础科学

专业: 生物学

单位: School of Biological Sciences, The University of Hong Kong,State Key Laboratory of Membrane Biology, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University,Division of Life Science, The Hong Kong University of Science and Technology,Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University

分类号: Q617

DOI: 10.26914/c.cnkihy.2019.038779

页码: 35

总页数: 1

文件大小: 144k

下载量: 4

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Cryo-EM Structure of the origin recognition complex bound to the essential elements of ARS DNA
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