Large-scale RNAi screening identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Large-scale RNAi screening identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

论文摘要

<正>Mutations in multiple key molecules regulating mitochondrial morphology could lead to severe human diseases.Through a large-scale in vivo RNAi screening that covered around a quarter of the Drosophila melanogaster genome(4000 genes),we identified 578 genes whose knockdown led to aberrant shapes or distributions of mitochondria.The complex analysis

论文目录

文章来源

类型: 国际会议

作者: Chao Tong

来源: Membrane Shaping and Remodeling by Proteins 2019-04-11

年度: 2019

分类: 基础科学

专业: 生物学,生物学

单位: MOE Key Laboratory for Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network,Life Sciences Institute,Zhejiang University

分类号: Q244

DOI: 10.26914/c.cnkihy.2019.049932

页码: 42

总页数: 1

文件大小: 136k

下载量: 2

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Large-scale RNAi screening identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis
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