Recent advances in the development of polydiacetylene-based biosensors

Recent advances in the development of polydiacetylene-based biosensors

论文摘要

Biosensors that effectively and selectively detect biomolecules and monitor biological processes have become an important component of biological and medical studies. Because they possess several attractive features, polydiacetylenes(PDAs) have been employed as frameworks for fluorometric and colorimetric sensors. PDAs are formed in their non-fluorescent blue-colored state by UV light induced polymerization of head group functionalized diacetylene monomers(DAs) and they undergo a transition to form fluorescent red-colored PDAs in response to a variety of stimuli. Importantly, by properly choosing a headgroup in the DA, the formed PDA can be designed to undergo a fluorescence/colorimetric change in response to a specific biological stimulus. This review summarizes recent advances that have been made in the development of PDA biosensors with an emphasis being given to design strategies and applications.

论文目录

文章来源

类型: 期刊论文

作者: Zhijie Zhang,Fang Wang,Xiaoqiang Chen

来源: Chinese Chemical Letters 2019年10期

年度: 2019

分类: 工程科技Ⅰ辑,信息科技

专业: 化学,自动化技术

单位: State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University

基金: financially supported by the National Key Research and Development Program of China (No. 2018YFA0902200),the National Natural Science Foundation of China (Nos.21722605,21978131 and 21878156),the Six Talent Peaks Project in Jiangsu Province (No.XCL-034),the Project of Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)

分类号: O657.3;O632.1;TP212.3

页码: 1745-1757

总页数: 13

文件大小: 25741K

下载量: 12

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Recent advances in the development of polydiacetylene-based biosensors
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