Visible-light-mediated external-reductant-free reductive cross coupling of benzylammonium salts with（hetero）aryl nitriles

论文摘要

Herein we report a novel visible-light-mediated external reductant-free reductive cross coupling for the construction of C sp2–C sp3 bonds. A variety of benzylammonium salts underwent selective coupling with（hetero）aryl nitriles to deliver important diarylmethanes under mild reaction conditions. Importantly, photocatalysts can be omitted for many cases, which might involve the electron donor acceptor（EDA） complex. Mechanistic studies indicated benzylic radicals might be involved as the key intermediates. Moreover, the in situ generated NMe3 via cleavage of C–N bond in ammonium salts acts as the electron donor,thus avoiding the use of external-reductant.

论文目录

• 1 Introduction
• 2 Experimental
• 3 Results and discussion
• 4 Conclusions

文章来源

类型: 期刊论文

作者: Meng Miao,Li-Li Liao,Guang-Mei Cao,Wen-Jun Zhou,Da-Gang Yu

来源: Science China(Chemistry) 2019年11期

年度: 2019

分类: 工程科技Ⅰ辑

专业: 化学

单位: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University,College of Chemistry and Chemical Engineering, Neijiang Normal University

基金: supported by the National Natural Science Foundation of China(21772129,21801176),the The National Basic Research Program of China from the Minstry of Science and Technology of China(2015CB856600),Sichuan Science and Technology Program(2019YJ0379),Neijiang Normal University(KF10076),the Fundamental Research Funds for the Central Universities(YJ201516)

分类号: O621.3

页码: 1519-1524

总页数: 6

文件大小: 518K

下载量: 1